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Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains
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  • 分类：S943[农业科学—水产养殖;农业科学—水产科学] TM714.3[电气工程—电力系统及自动化]
  • 作者机构：[1]CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China, [2]University of Chinese Academy of Sciences, Beijing 100049, China, [3]Network Information Center, Institute of Microbioiogy, Chinese Academy of Sciences, Beijing 100101, China, [4]Chinese Center for Disease Control and Prevention (China CDC), Beijing 102206, China, [5]Research Network of Immunity and Health (RNIH), Beijing Institutes of Life Science, Chinese Academy of Sciences,Beijing 100101, China
  • 相关基金：We thank Dr. Christopher J. Vavrickafor and Boris Tefsen for their critical reading and revision of the manuscript and Dr. Miles P. Dav- enport for his inspiring discussions. This work is supported by the National Natural Science Foundation of China （NSFC, Grant No. 31030030）, the National Basic Research Program （973 Program） （No. 2013CB531500） and the National Natural Science Foundation of China （Grant No. 81373141 ）. G.F.G. is a leading principal investigator of the NSFC Innovative Research Group （Grant No. 81321063）.
作者： Peipei Liu[1,2], Di Liu[3], Xi Yang[1,2], Jing Gaoai Ma3, Fangqing Zhaos, Xuyu Zhou~'2~, George F. Gao1'2'4'5~, Baoli Zhu~'2~[1,2], Yan Chen[1], Xue Xiao[1], Fei Liu[1], Jing Zou[1], Jun Wu[1], Juncai Ma[3], Fangqing Zhao[5], Xuyu Zhou[1,2], George F. Gao[1,2,4,5], Baoli Zhu[1,2]
关键词： T细胞受体, TCR, 人类, 基因重排, 表征, 链, 多样性, 工作集, TCR repertoire, next-generationsequencing, V/J usage, V-J pairing, CDR3, D-D fusion
中文摘要：

zhouxy@im.ac.cn （X. Zhou）, gaof@im.ac.cn （G. F. Gao） Correspondence： zhubaoli@im.ac.cn （B. Zhu）

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