我国是幽门螺杆菌(Helicobacter pylori,H.pylori)感染率较高的国家。儿童H.pylori感染不仅与消化性溃疡、慢性胃炎、胃癌等胃肠道疾病密切相关,还可能与多种胃肠道外疾病有关。但目前H.pylori感染的多种诊断方法各有利弊,各种治疗药物在不同地区显示出不同程度的耐药性。文章回顾了近年国内外儿童H.pylori感染流行病学、临床表现、诊断方法及其治疗方案的最新研究进展。
Helicobacter pylori(H.pylori)infection is prevalent in China.H.pylori infection plays a major role in pathogenesis of not only many gastrointestinal diseases,such as peptic ulcers,gastritis and gastric carcinogenesis,but also in some extra-gastrointestinal diseases.To date,diagnosis and treatment for H.pylori are not satisfying because various diagnostic methods showed their own advantages and disadvantages,and there is different degree of resistance to drugs.This article reviewed recent advantages on the epidemiology,clinic features,diagnosis and treatment of the H.pylori infection in children.