中文摘要：

目的：研究电视胸腔镜手术（VATS）中喷洒红霉素或滑石粉治疗非小细胞肺癌（NSCLC）转移性胸腔积液（MPE）的近期疗效。方法：将有MPE的NSCLC患者随机分为两组：A组VATS术中喷洒红霉素1．0g；B组喷洒滑石粉5．0g。对比两组胸引量、引流时间、不良反应与近期疗效。结果：两组拔管时间、胸引量均无统计学意义（P〉0．05）；总不良反应率红霉素组低于滑石粉组（P〈0．05）。结论：用红霉素作为VATS治疗MPE具有与滑石粉相仿的临床价值。

英文摘要：

Objective： To observe the short term effect and side reaction of spraying erythrocin or talc powder dur- ing VATS for patients with NSCLC and MPE. Methods ： All 44 patients with NSCLC and MPE were randomly divided into two groups. Group A was treated by VATS with spraying erythroein 1.0g in 21 cases. And group B was treated with spraying talc power 5.0g during VATS in 23 cases. The patients were given NP scheme chemotherapy after oper- ation during 8 days. The volume of pleural effusion, drainage duration and the side reaction were observed. Results ： There was no significant difference both in the volume pleural effusion and drainage duration between the two groups （P 〉0.05）. However, the total side reaction was more in the group B than that in the group A （P 〈0.05）. Con- clusion： Erythrocin can be as a new choice to treat MPE in VATS.