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中文摘要：
自噬（autophagy）是生物体活细胞用来维持自身平衡稳定的一个保守进程。已有研究表明，自噬与阿尔茨海默症（Alzheimer’Sdisease，AD）密切相关，并可能在AD的病程中起着关键作用。然而，迄今为止，其完整的作用机制仍未能得到深入的研究，自噬在AD中起到的作用仍然存在许多争议。近几年关于白噬在AD中作用和治疗方面有了一系列研究进展，陆续发现了一些能够通过调节自噬而改善AD的治疗手段，为相关的研究领域提供了一个新的认识和展望的平台。现就自噬在AD中的作用机制和相关治疗方法作一简要综述。
英文摘要：
Autophagy is a conservative process to maintain homestasis in cells. Studies have shown that autophagy and Alzheimer＇s disease （AD） are closely related and that autophagy may play a key role in the pathogenesis of AD. Up to now, however, the complete mechanism has not been thoroughly studied. Many disputes still remain about the role of autophagy in the pathogenesis of AD. In recent years, a series of progress in researches on the role of autophagy in AD process and its relevant treatment has been made, which provides a new understanding and an outlook for relevant studies. The mechanism of autophagy in AD and relevant methods are reviewed.
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