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Reaction of Ketene Dithioacetals with Pyrazolylcarbohydrazide: Synthesis and Biological Activities of Ethyl 5-Amino-1-(5'-methyl-1 '-t-butyl-4'-pyrazolyl)carbonyl-3-methylthio-1 H-pyrazole-4-carboxylate
  • ISSN号:1001-604X
  • 期刊名称:《中国化学:英文版》
  • 时间:0
  • 分类:O626.21[理学—有机化学;理学—化学]
  • 作者机构:[1]CollegeofChemistryandMolecularEngineering,QingdaoUniversityofScienceandTechnology,Qingdao,Shandong266042,China, [2]StateKeyLaboratoryofAppliedOrganicChemistry,LanzhouUniversity,Lanzhou,Gansu730000,China, [3]StateKeyLaboratoryofElemento-organicChemistry,NankaiUniversity,Tianjin300071,China
  • 相关基金:the Natural Science Foundation of Shandong Province (No. Y2003B01), the National Natural Science Foundation of China (No. 20172031) and State Key Laboratory of Applied Organic Chemistry of Lanzhou University.
中文摘要:

The title compound, C16H23N5O3S, ethyl 5-amino-1-(5'-methyl-1'-t-butyl-4'-pyrazolyl)carbonyl-3-methylthio-1H-pyrazole-4-carboxylate (5) has been synthesized by the treatment of ethyl 2-cyano-3,3-dimethylthioacrylate with 1-t-butyl-5-methyl-4-hydrazinocarbonylpyrazole (4) in refluxed ethanol. The possible mechanism of the above reaction was also discussed. The results of biological test show that the title compound has fungicidal and plant growth regulation activities.

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期刊信息
  • 《中国化学:英文版》
  • 主管单位:
  • 主办单位:中国化学会
  • 主编:
  • 地址:上海市枫林路354号中科院上海有机化学研究所
  • 邮编:200032
  • 邮箱:
  • 电话:021-54925243
  • 国际标准刊号:ISSN:1001-604X
  • 国内统一刊号:ISSN:31-1547/O6
  • 邮发代号:4-646
  • 获奖情况:
  • 中国期刊方阵“双高”期刊
  • 国内外数据库收录:
  • 美国化学文摘(网络版),荷兰文摘与引文数据库,美国科学引文索引(扩展库),日本日本科学技术振兴机构数据库,英国英国皇家化学学会文摘
  • 被引量:175