中文摘要：

目的通过研究不同程度视敏度障碍者模式翻转视诱发电位（pattern reversal visual evoked poten-tials,PRVEP）P100的特征,分析不同视角光刺激下与视敏度之间的相关性。方法选用视敏度分别为0.2、0.4、0.6、0.8、1.0志愿者共100只眼,采用不同空间频率（8°到7.5′）的翻转图形刺激,在Oz点记录PRVEP并测量P100的潜伏期与波幅。应用SPSS 13.0软件对数据进行统计学分析。结果 P100潜伏期及波幅均与视角之间存在曲线关系,0.2视敏度组在1°时P100潜伏期达最短、波幅达峰值,余视敏度组均在30′视角达最佳值;P100潜伏期和波幅均与视敏度之间存在线性相关,随着视敏度的增加,P100呈现潜伏期逐渐缩短、波幅逐渐增高的趋势,并分别建立了潜伏期、波幅与视敏度之间的回归模型。结论通过PRVEP检查法,运用各视敏度组最佳刺激视角及借助回归方程推算视敏度,可以作为视敏度评定的客观、精确的手段。

英文摘要：

Objective To explore pattern reversal visual evoked potential（PRVEP） P100 components in the patients with different visual acuity and the correlation of P100 components with visual acuity using different visual simulation angles.Methods PRVEPs were recorded at Oz point in the patients（100 eyes） with different visual acuity including 0.2,0.4,0.6,0.8 and 1.0 and induced by pattern reversal visual simulation with the different spatial frequencies（check sizes： 8°-7.5′）.The latency and amplitude of components P100 were analyzed and statistical analysis was performed using SPSS 13.0 software.Results The latency and amplitude of P100 wave showed a curvilinear relationship with check sizes.With check size 1° simulation in 0.2 visual acuity group,the P100 latency reached to the minimum and the P100 amplitude showed peak value.Other groups displayed the best value with check size 30′.The P100 latency and amplitude showed a linear correlation with visual acuity.With the increase of visual acuity,the P100 wave latency decreased and the amplitude increased gradually.Regression models between visual acuity and the P100 wave latency and amplitude were also established.Conclusion The regression functions can be an objective and accurate method to evaluate the visual acuity based on the better simulation angles using PRVEP examination.