中文摘要：

本文以3-巯基丙酸（3-Mercaptopropionic Acid,MPA）为稳定剂,采用水相合成法制备了Mn掺杂ZnS量子点（Mn∶ZnS QDs）,基于Mn∶ZnS QDs的室温磷光性质,盐酸巴马汀（Palmatine Hydrochloride,PaH）可与Mn∶ZnS QDs发生静电作用,使得Mn∶ZnS QDs发生室温磷光猝灭效应,从而发展了一种高效、快速检测人体体液中痕量PaH的新方法。实验结果表明,当PaH的浓度在0.75~30μmol/L范围时,其浓度与室温磷光猝灭强度（ΔIRTP）呈良好的线性关系,相关系数为0.996,检出限为0.35μmol/L,加标回收率为94.0%~103.3%。

英文摘要：

Mn doped ZnS quantum dots（QDs）were prepared through water phase synthesis method by taking 3-mercaptopropionic acid（MPA）as a stabilizer.Based on the room temperature phosphorescence of Mn doped ZnS QDs,electrostatic interaction was occurred between palmatine hydrochloride（PaH）and Mn doped ZnS QDs,resulting in the quenching effect of room temperature phosphorescence to Mn doped ZnS QDs.Therefore,an effective and rapid method was developed to detect trace PaH in human body fluid.When the PaH concentration was 0.75-30μmol/L,agood linear relationship was represented between it and phosphorescence quenching intensity（ΔIRTP）with the correlation coefficient of 0.996,and the detection limit and recovery is 0.35μmol/L and 94.0%-103.3%,respectively.