中文摘要：

胰蛋白酶抑制剂（TI）是对胰蛋白酶具有抑制作用的一类物质,生理作用广泛,不仅可以抑制多种酶的活性,而且通过抑制细胞浸润、促进细胞凋亡,在抗肿瘤方面发挥了很大的作用.Wnt信号通路是调控细胞生长、增殖和凋亡的关键通路,在肿瘤发生、发展中起着重要的作用.现就TI对Wnt信号通路及肿瘤细胞凋亡影响的研究进展进行综述

英文摘要：

The trypsin inhibitor is a kind of substance that can inhibit trypsin activity.It shares extensive physiological roles.The trypsin inhibitor not only inhibits the activities of many enzymes,but also has significant anti-cancer effects by suppressing cell invasion and promoting cell apoptosis.Wnt signaling pathway involves in the regulation of cell growth,proliferation and apoptosis.It also plays an important role in tumor development.This review focuses on the impacts of trypsin inhibitors on Wnt signaling pathway and tumor cell apoptosis