中文摘要：

目的：探讨膳食摄入对血清apoA-Ⅳ水平的影响，以进一步阐明apoA-Ⅳ调节摄食和能量平衡的作用机理。方法：选取山东省淄博市农村和济南市社区居民389例，采用酶联免疫吸附法（ELISA）检测空腹12h血清apoA-Ⅳ的水平；采用3d膳食记录法获得膳食摄入量。所有数据使用SPSS12．0版软件进行分析。结果：apoA-Ⅳ水平与脂肪、膳食纤维、碳水化合物、蛋白质摄入量呈负相关关系（P〈0．05），高脂膳食者血清apoA-Ⅳ水平显著低于低脂膳食者（P〈0．05）。结论：高脂肪摄入是影响血清apoA-Ⅳ水平的主要因素。

英文摘要：

Objective： To investigate the effect of dietary fat intake on human serum apolipoprotein（ape） A-Ⅳ levels and further illustrate the regulation of food intake and bodyweight gain. Methods： This investigation was conducted in 389 subjects aged 7-70 years from Zibo and Jinan city in Shandong Province. The serum apoA-Ⅳ concentrations were measured by enzyme-linked immunosorbant assays （ELISA）. Dietary intake was estimated from 3-day food record. Statistical analyses were performed with SPSS 12.0. Results： Senan apoA-Ⅳlevels were negatively correlated with dietary fat, fiber, carbohydrate, and protein intake（P 〈0.05）. Humans chronically consuming a highfat diet initially developed significantly lower serum apoA-Ⅳ levels than those of a low-fat diet. Conclusion： A highfat diet intake is the primary factor to affect serum apoA-Ⅳ levels.