研究了转mtlD/gutD双价基因稻米对大鼠的性腺毒性。通过对大鼠90d喂养观察及对各组动物的睾丸和卵巢进行组织切片检查,未见有意义的病理改变。比较雌性大鼠的性成熟、雄性大鼠的精子畸变率及雌雄大鼠的性激素水平,各实验组与对照组均无显著差异(P〉0.05)。结果初步表明用转mtlD/gutD双价基因水稻秀水11品系T18—7—8—1稻米喂养大鼠90d对大鼠性腺器官的结构和功能无明显影响。
Sexual gland toxicity of transgenic rice with mtlD/gutD gene (rice line T18-7-8-1) in rats was studied. The resuits showed that no pathological changes were found in organs such as testis and ovary in rats in both experimental and control groups in a 90-day-feeding test by histological section examination. No significant differences( P〉0. 05) were observed on maturation of sexual gland in females, aberrant sperm rate of males and sexual hormone of rats between the experimental groups and the control.