以1-苄基—3-甲基咪唑四氟硼酸(IL1)和1-已基—3-甲基咪唑双(三氟甲基磺基)亚胺(IL2)及废水为混合物组分,以Vibrio qinghaiensissp.-Q67为指示生物,采用均匀设计射线法设计不同浓度配比的IL1-IL2混合物体系及IL1-IL2-废水的混合物体系,应用微板毒性分析法系统测定这些混合物体系的浓度-效应数据,并以浓度加和与独立作用模型为加和参考模型分析毒性相互作用.结果表明:IL1-IL2的混合物体系具有拮抗或加和作用,且混合物毒性(pEC50值)与其中IL1的浓度比具有良好的线性关系;IL1-IL2-废水的混合物体系具有明显的协同或加和作用,且混合物pEC50值与其中废水的浓度比具有良好的线性关系.
By selecting two ionic liquids (ILs), l-benzyl-3-methylimidazolium tetrafluoroborate (IL1) and l-hexyl-3-methyl-imidazolium bis (trifluoromethylsulfony)imide (IL2) , and wastewater (WW) as mixture components, two mixture systems, one between ILl and IL2 and the other among IL1,IL2 and WW with different concentration ratios (p/s) , were designed by the uniform design ray procedure. The toxicities of single components and the mixtures to Vibrio qinghaiensis sp.-Q67 (Q67) were determined by the microplate toxicity analysis. The toxicity interaction within mixtures was analyzed by using the concentration addition and independent action as reference models. It was showed that the mixtures between ILl and IL2 exhibited antagonistic or additive interaction and the combined toxicity ( pEC50 ) was well correlated with the concentration percentage of IL1 , while the mixtures among IL1, IL2 and WW displayed synergistic or additive interaction and the combined toxicity ( pEC50 ) was well correlated with the concentration percentage of WW.