中文摘要：

姜黄素具有广泛的药理活性，其作为治疗多种疾病的潜力药物的研究正越来越多的引起关注。多个临床I期试验已证实，姜黄素口服安全且耐受性好；药动学表明，姜黄素口服不易吸收，生物利用度低。研究显示，姜黄素治疗乳腺癌、结肠癌、肠易激综合征、风湿性关节炎及动脉粥样硬化等有疗效。现总结了姜黄素临床研究的报道，以冀为姜黄素的应用研究提供参考。

英文摘要：

Curcumin has been described as a potential agent for many diseases and is attracting much more attention due to its various pharmacological activities. Several phase I trials have demonstrated curcumin is well tolerated and safe. The pharmacokinetic studies of curcumin indicated in general a low bioavailability of curcumin following oral application. Extensive research has shown that curcumin has pharmacological efficacy in breast cancer, colon cancer, IBS, rheumatoid arthritis, atherosclerosis, and so on. This article summarized the related materials on clinical research of curcumin, and gave a review for application and study in the future.