口服结肠靶向给药系统在药物转运和治疗结肠局部疾病方面具有重要作用。本文总结了口服结肠靶向给药系统近年来的研究概况,并对结肠靶向药物制剂的体内、外评价方法作一介绍。
Oral colon-specific drug delivery system (OCDDS) has gained increased importance for the delivery of drugs for the treatment of local diseases associated with the colon in recent years. In this article, the recent development of OCDDS was summarized, and in vitro and in vivo evaluation methods were also discussed.