中文摘要：

本文阐述了精神分裂症的发病机制，提出了用新型毒品氯胺酮建立精神分裂症SD大鼠动物模型，并提出用免疫组化技术对大鼠海马及前额叶皮质区的精神分裂症阳性细胞进行定位的方法，同时也讲述了免疫组化技术的应用，这将为精神分裂症的鉴定及个性化治疗提供依据。

英文摘要：

This paper described the pathogenesis of schizophrenia,proposed the use of new drugketamine to establish schizophrenia SD rat animal model,and proposed by immunohistochemistry on the hippocampusand prefrontal cortex of schizophrenia positive cells,and the application of immunohistochemistry,which will provide the basis for the identification and personalized treatment of schizophrenia.