目的:研究中医治疗幽门螺旋杆菌对幽门螺杆菌与颈部血管斑块疗效的影响。方法:将2012年9月—2015年9月期间我院收治的138例颈动脉粥样硬化斑块合并Hp感染的患者随机分成中医组与对照组,中医组采用中药汤剂联合穴位敷贴治疗,对照组采用三联抗疗法治疗,比较两组对Hp的根除率,治疗前后的颈部血管斑块厚度以及脂质代谢水平。结果:中医组治疗结束后对Hp的根除率明显的高于对照组,1年内的Hp再感染率明显的低于对照组,比较差异具有显著性(P〈0.05);治疗3个月后,中医组的颈动脉斑块厚度明显的小于对照组,比较差异具有显著性(P〈0.05);治疗后,中医组的TC、TG、LDL-C和Hcy水平明显的低于对照组,HDL-C水平显著的高于对照组,比较差异具有显著性(P〈0.05)。结论:中医治疗Hp不仅对根除Hp效果显著,对改善脂质代谢,治疗颈动脉斑块也具有重要的意义,且安全性高。
Objective :To study the effect of Chinese herbal medicine on Helicobacter pylori(Hp) in the treatment of Hp and neck plaque. Methods :Between September 2012 and September 2015,138 patients with carotid atherosclerotic plaques and Hp infection were randomly divided into the TCM group and the control group. TCM group was treated by traditional Chinese medicine decoction combined with acupoint application therapy while the control group was treated with triple anti - therapy. The eradication rate of Hp, thickness of carotid artery plaque and lipid metabolism before and after treatment were compared. Results : The eradication rate of Hp was significantly higher in the TCM group than that in the control group, and the infection rate of Hp in 1 year was significantly lower than that in the control group ( P 〈 0. 05 ). After 3 months of treatment, the thickness of the carotid artery was significantly smaller in the TCM group than those in the control group (P 〈 0. 05). After treatment, TC, TG, LDL - C and Hcy levels in the TCM group were significantly lower than those in the control group and the HDL - C level was significantly higher than that of the control group. Conclusion : Chinese medicine in treatment of Hp not only has significant effect for eradicating Hp, but also is important for improving lipid metabolism and treating carotid plaque, and it is safe.