中文摘要：

许多肿瘤依赖谷氨酰胺（Gin）供能，Gln代谢被认为是除Warburg效应之外又一重要的肿瘤细胞能量代谢特征之一。以正电子发射计算机断层扫描（PET）为代表的核医学分子示踪技术为肿瘤的早期诊断和预后提供了很好的手段，利用PET显像技术可以无创地探测肿瘤Gin代谢区域，为优化肿瘤诊断和治疗方案提供了新策略。

英文摘要：

Many tumors depend on glutamine for energy. Glutamine metabolism is recognized as a dis- tinetive feature in addition to Warburg effect in tumors. Nuclear medicine molecular tracer techniques represen- ted by positron emission tomography （PET） provide a good means for early diagnosis and prognosis of tumors. PET imaging can detect glutamine metabolism region in tumors noninvasively, which can provide new diagnosis and therapeutics for glutamine-addicted tumors.