中文摘要：

系统介绍了近年来手语加工的脑损伤以及脑成像研究，重点阐述了如下几个问题：1）手语基本情况介绍；2）研究手语神经机制的2种角度——脑损伤角度和脑成像角度；3）手语理解和产生的神经机制；4）手语研究中有待于进一步解决的关键问题．

英文摘要：

This article reviews neural mechanism for sign language processing, in regards to both sign language aphasia and brain image. It focuses on： 1） basic information on sign language; 2） two main methods involved-brain damaged aphasia and brain imaging; 3） neural organization in regards to sign language comprehension and production. A number of critical issues in need of further investigation are addressed.