提出了一种以磁铁固定微铁丝为模板的利用原位控制聚合制作无缝高聚物微流控芯片的新方法, 并用其制备了复杂流道PMMA芯片和内埋玻璃纤维丛的PMMA混合芯片, 实现了在雷诺数为22时的理想混合. 所建立的方法无需超净环境, 操作简单, 成本低且易推广.
A new method was established for the fabrication of seamless polymer microfluidic chips. By the method, seamless PMMA microfluidic chips were easily fabricated by in situ polymerization of monomer solution casting on a channel mold temporarily fixed with pieces of fine iron wires by a magnet beneath the polymerizing container. Seamless channels were formed by bonding two pieces of 70%--80% polymerized PMMA slides of which one was preprinted with channels. Glass-fibers-embedded microfluidic mixers have also been fabricated in the same way where a section of about 2 mm glass-fiber bundle was inserted between two wires before casting polymerizing solution. With such a mixer, ideal mixing was easily achieved at Re ≥ 22. This method features easy manipulation and low cost, it fits ordinary chemistry laboratories, requiring no clean room or lithographic facilities.