果酸是一系列α位含有羟基的羧酸的统称,其分子能够穿过角质层被皮肤吸收,可促进表皮细胞的新陈代谢、真皮胶原合成,广泛应用于医学美容和临床治疗中,成为目前化学换肤术的主要成分。果酸换肤可用作痤疮、黄褐斑、光老化等辅助治疗,是一种快速、安全、有效的临床治疗方法,本文对果酸的种类、临床应用、换肤术后注意事项及不良反应等进行了综述。
Alpha hydroxy acid(AHAs) is the common name of a series of carboxylic acid with hydroxy in α-position, the molecular can be easily absorbed in skin through the stratum corneum. It can promote metabolism of epidermal cell and dermal collagen synthesis. It is frequently used in cosmetology and clinic treatment. AHAs become the most popular chemical compounds for chemical peels. Chemical peels are a fast, safe and effective clinic treatment that can be as adjunct therapies for acne, melasma, photoaging and so on. The species, application, considerations, adverse effects of glycolic acid in dermatology were summarized.