应激性溃疡是临床危急性疾病的常见并发症,其发病机制复杂,发病率及病死率较高。通过动物模型来研究应激性溃疡的发病机制已成为热点。本文概括了多种动物的应激性溃疡模型的实验方法,阐明了各动物模型的优缺点。最后,作者也对应激性溃疡模型的建立提出了自己的看法和见解。
The stress ulcer is a frequent complication in clinical critical diseases. Stress ulcer has a high rate of incidence and mortality, its pathogenesis is complex. It is getting popular to investigate the pathogenesis of stress ulcer by building the animal model. This article reviews the empirical methods of various animal models of stress ulcer and summarizes the advantages and disadvantages of each type of animal model. In the end, the author provides a prospect for the animal model of the stress ulcer in this review.