中文摘要：

急性肺损伤/急性呼吸窘迫综合征（ALI/ARDS）是临床上最常见的急危重症,其发病机制错综复杂,缺乏主动性治疗措施,病死率高。研究表明,核因子κB（NF-κB）为一种诱导型核转录因子,在ALI/ARDS发展过程中发挥极为广泛的功能,并与炎症反应具有密切的关系。现就ALI/ARDS、NF-κB信号转导通路及两者的关系作一简要的论述。

英文摘要：

Acute lung injury/acute respiratory distress syndrome is one of the most common clinical emergencies, with a complex pathogenesis, the lack of active treatment measures, high mortality. Nuclear factor kappa B is an inducible nuclear transcription factor. Activation of nuclear factor kappa B signal transduction pathway is involved in a wide range of functions in acute lung injury/acute respiratory distress syndrome and it is closely related with inflammation. This review is about acute lung injury/acute respiratory distress syndrome, nuclear factor kappa B and the relationship between acute lung injury/acute respiratory distress syndrome and nuclear factor kappa B signaling pathway.