精确控制材料泡孔孔径和泡孔密度在组织工程支架材料的制备中尤为重要。本文采用固态无溶剂气体发泡法制备了103μm~8μm不同孔径的聚乳酸发泡材料,利用扫描电子显微镜技术和傅里叶变换红外光谱技术研究了不同孔径的聚乳酸发泡材料的泡孔形貌和官能团特征。结果显示随着饱和压力的增大,材料的泡孔孔径减小,泡孔密度增大,泡壁厚度减小,分子振动受到限制。
It is especially important to control bubble diameter and cell density accurately in the preparation of tissue engineering scaffold (TES) materials. The technologies of scanning electron microscopy (SEM) and fourier transform infrared spectroscopy (FTIR) were used to analyze the cell structure and functional group vibrations of Polylactic acid (PLLA) foams with the cell sizes from 103 to 20μm fabricated using a solvent free solid-state gas foaming method. It was observed that PLLA foams with smaller cell size, lar- ger cell density and thinner cell wall thickness could be fabricated at higher saturation pressure.