中文摘要：

目的：初步研究山药粉和直压辅料的流动性与压缩特性。方法：对山药粉和直压辅料作粉体综合特征测试以描述其流动性，从压缩过程与机械性质等方面来描述山药粉的压缩特性，同时使用数学模型方法对压缩过程进行评价和分析。结果：山药粉体可压性非常差，虽然Kankita方程显示二者有较接近的特性，但孔隙率-上冲压力关系和Heckel方程却显示二者较大的区别，评价粉体时需要综合分析与测试。结论：与粉体特征有关的参数或数学模型可表征中药粉体与直压辅料的特性，但有待于明确物理性质与药物粉体的压缩成形性之间的关系或规律性。

英文摘要：

Objective： To preliminary study on mobility and compression characteristics of D opposita powder and direct compression accessories. Method： Mobility of D. opposita powder and direct compression accessories were described by powder comprehensive characteristic test, compression characteristics of D. opposita powder was described by compression process and mechanical properties, at the same time, mathematical model method was used to evaluate and analyze compression process. Result： The compressability of Dioscorea opposita powder is poor. Though the compression characteristics of the two have similarities in Kawkita equation, they have greater differences in a great deal of respects in porosity-pressure relationship and Heckel equation. So the evaluations need comprehensive analysis and test. Conclusion： Related parameter of powder characteristics or mathematical model could be characterized features of Chinese medicine powder and direct compression excipient, however, relationship or regularity between physical properties and compression formability of drug powder were still need to be clarified.