中文摘要：

micro/-nanoscaled 功能的 biointerfaces 引起了他们的关键单位元素的许多兴趣介绍唯一的功能。到目前为止描述这个过程的整个图画仍然是困难的。越来越多的证据开始正在支持 mirco/-nanotopography-coupled-mechanical (TCM ) 的理论行动进功能的 biointerfaces。此处，我们试图在改变的 micro/-nanoscaled 上加亮 TCM 行动功能的 biointerfaces，也就是由介绍界面的机械行为组织完成 micro/-nanoscaled 的更好的理解。在这篇文章，在自然的 air/liquid/solid-phase biointerfaces 上的 TCM 上的最近的前进在在 micro/-nanoscales 的 vivo TCM 行为，在 micro/-nanoscaled 的 TCM 有生活房间和地形学的人工的表面，界面的弯曲，力学被考察。TCM 行动的某些新概念基于空间弯曲，医学上功能的 biointerfaces 和 biomechanopharmacology 也被建议。

英文摘要：

The micro/-nanoscaled functional biointerfaces aroused much interest of their key unit element to present unique functions. So far it is still difficult to describe the whole picture of this process. More and more evidences are begin- ning to support the theory of ＂mirco/-nanotopography-cou- pied-mechanical （TCM） action＂ into functional biointerfaces. Herein, we aim to highlight TCM action on varied micro/- nanoscaled functional biointerfaces, namely to achieve better understanding of micro/-nanoscaled structures by introducing interfacial mechanical behaviors. In this article, recent pro- gressions on ＂TCM on air/liquid/solid-phase biointerfaces in nature＂, ＂in vivo TCM behaviors at micro/-nanoscales＂, ＂TCM in micro/-nanoscaled artificial surface with living Cells＂ and ＂topography, interfacial curvature, mechanics＂ are reviewed. Certain new concepts of ＂TCM action based on spatial curvature＂, ＂medically functional biointerfaces＂ and ＂biomechanopharmacology＂ are also proposed.