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574例结核病病例细菌学检验结果分析
  • ISSN号:1003-9961
  • 期刊名称:《疾病监测》
  • 时间:0
  • 分类:R52[医药卫生—临床医学;医药卫生—内科学]
  • 作者机构:[1]传染病预防控制国家重点实验室,中国疾病预防控制中心传染病预防控制所,北京昌平102206, [2]陕西省西安市疾病预防控制中心
  • 相关基金:本论文受到国家自然科学基金项目30471526和国家“十五”重点攻关项目200IDEA10007的资助.传染病预防控制国家重点实验室、和中国疾病预防控制中心传染病预防控制所和陕西省西安市疾病预防控制中心在本论文享受同等贡献.
中文摘要:

目的了解西安市分支杆菌病原菌感染的流行状况,为制定结核病防治措施提供科学依据。方法采用流行病学抽样调查方法,选取陕西省西安市为调查点,于2005年5-8月对其13个区级结防所就诊的所有病人进行调查,每个病人收集三份痰标本。采用痰涂片和痰培养法检测病人痰标本,鉴别培养基培养法鉴定分支杆菌菌种。结果574位病人,涂片阳性113人,阳性率为19.69%,培养阳性病人150人,阳性率26.13%。后者明显高于前者,两者之间的差异具有显著统计学意义(x^2=360.50,P〈0.01),两者联合阳性率为26.83%。从137例病例痰标本中分离到251株分支杆菌菌株,结核分支杆菌、牛分支杆菌、非结核分支杆菌(NTM)和混合感染的比例分别是67.88%、5.84%、11.68%、14.60%。结论细菌培养法可明显提高阳性率;NTM感染流行状况应予以足够的重视。

英文摘要:

Objective This study was designed to investigate the prevalence situation of Mycobacterium infection in Xi'an City, Shanxi Province and provide a scientific basis of tuberculosis prevention and therapeutic measure. Methods Xi'an City was choosed as the investigatory city for this study and the sample investigation was carded out. All the sputum specimens were collected from the suspected patients who suffered from TB. Sputum samples were tested by smear slide microscopy and culture method. The clinical isolate strains were determined to the species of Mycobacterium by the identified media. Results 574 suspect patients were tested. The number of smear positive and culture positive was 113 (19.69%) and 150 (26.13%) respectively. There was significant difference between the two methods (x^2=360.50,P〈0.01). 154 patients were diagnosed with tuberculosis by smear or culture positive result, the positive rate was 26.83%.251 strains isolated from 137 patients in which the infection rate was 67.88%, 5.84%, 11.68% and 14.60% by MTB, M.bovis, NTM, and mix infected by two species of mycobacterium respectively. Conclusion The sensitivity of sputum culture is much better than that of smear slide microscopy method. The prevalence situation of NTM infection must be pay more attention especially.

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期刊信息
  • 《疾病监测》
  • 中国科技核心期刊
  • 主管单位:国家卫生部
  • 主办单位:中国疾病预防控制中心
  • 主编:徐建国
  • 地址:北京市昌平区昌百路155号
  • 邮编:102206
  • 邮箱:jbjc@icdc.cn
  • 电话:010-58900732
  • 国际标准刊号:ISSN:1003-9961
  • 国内统一刊号:ISSN:11-2928/R
  • 邮发代号:82-859
  • 获奖情况:
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,中国中国科技核心期刊
  • 被引量:18705