中文摘要：

目的：分析和评价常规脑电图（EEG）在孤独症谱系障碍（ASD）儿童综合康复治疗中的临床价值。方法：36例2～7岁ASD患儿，进行综合康复治疗3个月，比较治疗前后常规EEG、临床症状、智力和语言水平的变化情况。结果：治疗前有异常或界限EEG表现的ASD患儿治疗后ABC量表总分及感觉、交往、生活自理因子得分，CARS量表总分，韦氏智力测验中操作智商和总智商，0-6岁儿童神经心理发育量表（儿心量表）中智龄、精细动作、适应能力、语言和社交行为得分，S—S语言发育迟缓评定量各项得分均较治疗前有明显改善（P〈0．05），且有5例患儿EEG表现转为正常（P〈0．01）。而治疗前EEG正常表现的ASD患儿治疗后仅CARS量表分，操作智商和总智商，S-S语言发育迟缓量表中语言理解分和总分有改善（P〈0．05），对智力发育（4岁以下）、临床症状（家长访谈角度）和言语水平（言语表达、言语符号、动作性课题）改善不佳（P〉0．05）。结论：常规EEG检测可作为一种评价康复治疗后脑功能变化的方法，也可用于指导孤独症儿童综合康复治疗方案的选择和疗效的预测。

英文摘要：

Objective： To analyse and evaluate the clinical value of routine EEG in comprehensive rehabilitation therapy of children with autism spectrum disorder （ASD）. Methods： Routine EEG, clinic symptom, intelligence and language skills were measured before and after 3 months of comprehensive rehabilitation therapyin 36 children with ASD aged 2-7 years old. Results ： Scores of total and most subscales of autism behavior checklist （ABC）, childhood autism rating scale （CARS）, wechsler intelligence scale for children （WISE）, neuropsychological development examination table for children and language retardation screening and diagnosing scales （S-S） were increased significant in children with ASD and abnormal or limited EEG before the treatment （P 〈 0.05）. Moreover, abnormal EEG performance was became normal in 5 children （P 〈 0.01）. But the improvement of scores in children with normal EEG were only manifested in total of CARS, of S-S （P 〈 0.05）. There were no significant improvement WISC, S-S and PIQ of WISC, language comprehension on intelligence of children （age 〈 4）, clinical symptoms and verbal skills, including verbal expression, verbal symbol and motor subjects （P 〉 0.05）. Conclusion： Routine EEG is a common which can be also therapy. method of appraising the change of the brain function after comprehensive rehabilitation therapy, used to guide the choice of treatment and predict the efficacy of the comprehensive rehabilitation