中文摘要：

目的对兔颈总动脉侧壁型动脉瘤模型进行改进,以评价建模的成功率及支架植入后颈总动脉的通畅率。方法取新西兰大白兔20只,饲养1周后行左侧颈内动脉结扎。1个月后行颈部3.0 T MRA检查评价颈动脉与椎动脉的变化情况。采用间断式外翻缝合法吻合静脉囊与颈总动脉,建立侧壁型动脉瘤。在植入覆膜支架前、术后即刻、3个月、6个月行血管造影。结果 20只实验兔均顺利行左侧颈内动脉结扎。MRI示结扎前右颈总动脉中段平均直径为（2.35±0.08）mm,结扎后1个月右颈总动脉中段平均直径为（2.89±0.22）mm,与术前比较差异有显著统计学意义（P〈0.01）。MRA示17只兔右颈总动脉明显增粗,而双侧椎动脉略增粗;3只兔颈总动脉增粗不明显,而双侧椎动脉明显增粗。建立兔颈总动脉囊状动脉瘤模型17只,术后均健康成活。DSA示覆膜支架植入前所有动脉瘤及右颈总动脉通畅,4个动脉瘤腔内有少量血栓形成,但无自发性完全闭塞。Willis或镁合金覆膜支架植入术后即刻造影示动脉瘤闭塞,右颈内动脉通畅。术后3个月DSA示16只兔右颈内动脉通畅,1只闭塞。术后6个月DSA示16只兔右颈内动脉通畅。动脉瘤模型的成功率为100%（17/17）,覆膜支架植入后右颈总动脉的通畅率为94.1%（16/17）。结论兔颈总动脉侧壁型动脉瘤模型制作的改进提高了动脉瘤模型的成功率及覆膜支架植入后右颈总动脉的通畅率。

英文摘要：

Objective To improve the preparation procedure of lateral wall aneurysm model of common carotid artery in experimental rabbits, and assess its success rate and patency rate of the common carotid artery after receiving stent placement. Methods A total of 20 New Zealand rabbits were used for this study. The left common carotid artery of the New Zealand rabbit was ligated after breeding for one week. The arteries of the neck were examined with 3.0 T MRA to observe the changes of carotid and vertebral arteries one month after ligation. Finally, an anastomosis between venous pouch and common carotid artery was accomplished by using interrupted extroversion suture method with 6- 0 microsuture, and the lateral wall aneurysm model of common carotid artery was thus established. Before, immediately after and 3, 6 months after the stent implantation the carotid angiography was carried out to check the results. Results The left common carotid arteries were successful ligated in all twenty New Zealand rabbits. Before and one month after the ligation the mean diameter of right carotid middle segment was（2.35 ± 0.08） mm and（2.89 ± 0.22） mm respectively, the difference was statistically significant（P〈0.001）. MRA performed one month after ligation revealed that in 17 rabbits the right carotid was strikingly thickened and bilateral vertebral arteries were slightly thickened; in 3 rabbits no obvious thickened carotid was found, while bilateral vertebral arteries were evidently thickened. The lateral cystic aneurysm models in common carotid artery were established in 17 rabbits, and all the model rabbits were healthy and alive. DSA—983 —performed before the implantation of covered- stent showed that all aneurysms were clearly displayed and right carotid was patent. In 4 cases, a small amount of thrombus could be seen within the aneurysmal cavity, but no spontaneous total occlusion of the aneurysm was observed. Angiography performed immediately after the implantation of Willis or magnesium alloy- covered stent rev