中文摘要：

背景 Typhoid/paratyphoid 发烧( TPF )在 Guizhou.We 是地方性的进行了小浪分析和枪兵的等级关联分析在贵州在 TPF 感染上探索气象学的变化的影响，在估计与我们检验了的 TPF epidemics.Methods 联系的风险因素的一次尝试在在贵州和温度的 TPF 发生之间的协会，用 24 年从 TPF 发生的 1984～2007 .Periodicities 和气候因素的影响的数据的 降水和相对湿度

英文摘要：

Background Typhoid/paratyphoid fever （TPF） is endemic in Guizhou.We conducted wavelet analysis and Spearman＇s rank correlation analysis to explore the impact of meteorological variations on TPF infection in Guizhou,in an attempt to assess the risk factors associated with TPF epidemics.Methods We examined the association between TPF incidence in Guizhou and temperature,precipitation and relative humidity using 24 years of data from 1984 to 2007.Periodicities of TPF incidence and the impact of climate factors on the TPF were detected by Spearman＇s rank correlation and wavelet analysis,Results Temperature and precipitation with a 1-month lag were positively correlated with the monthly incidence of TPF.The multiyear incidence pattern of TPF in Guizhou was explicitly periodic.Moreover,the association and driving effect of precipitation on TPF were observed,and the results showed that the incidence of TPF in Guizhou had a closer correlation with precipitation than with temperature.Conclusions Safe water supply is the key issue for TPF control in Guizhou.Moreover,climate variation might impact the enteric infections,which may inform policy assessment for TPF control in Guizhou.