中文摘要：

红细胞生成素（erythropoietin,EPO）临床是应用于慢性肾脏病患者贫血治疗,一部分患者因铁缺乏、炎症、氧化应激等因素出现红细胞生成素低反应的现象,影响红细胞生成素治疗效果,充分透析、补充营养、使用长效红细胞生成素等对策可改善红细胞生成素低反应。

英文摘要：

Erythropoietin （EPO） is used in clinical treatment of anemia in chronic kidney disease patients. Hyporesponsiveness of EPO occurs in some patients due to iron deficiency, inflammation, oxidative stress, etc. Adequate dialysis, improvement of nutritional status, and the use of long-acting EPO may have ef- fect on the EPO hyporesponsiveness.