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The prodrugs of L­guanosine analogs:design, synthesis and anti­HIV activity
  • 期刊名称：J. Chin. Pharm. Sci.
  • 时间：0
  • 页码：335-341
  • 相关项目：含氟生物活性物质的分子设计与合成
作者： Jun-Fang Lu, Lu-Jia Xie , Mou Cao, Zhu Guan*|Ying Guo, Zhen-Jun Yang*, Li-He Zhang|
同期刊论文项目
含氟生物活性物质的分子设计与合成
期刊论文 122
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Stereoselective Reformatskii-Claisen rearrangement: synthesis of 2 ';,3 ';-dideoxy-6 ';,6 ';-difluor
Methyl carboniumion migration during the reaction of 4-chloro-5-methoxyl-3(2H)-pyridazinone with tri
Synthesis of Fluorinated Chiral Amines Using N-tert-Butylsulfinyl Imines.
Highly Diastereoselective Synthesis of α-Difluoromethyl Amines from N-tert-Butylsulfinyl Ketim
Nucleophilic Difluoromethylation of N,N-Acetals with TMSCF2SO2Ph Reagent Promoted by Trifluoroacetic
Synthesis of Photochromic 1,2-Dithienylethene Derivative with a 2,2,5,5-Tetrafluoro-2,5-dihydrofuran
Cu(II)-mediated methylthilation of aryl C-H bonds with DMSO
A Practical Approach to Synthesize the C(9)-C(24) Fragment of (+)-Discodermolide
Nucleophilic (phenylsulfonyl) difluoromethylation of alkyl halides using PhSO2CF2SiMe3: preparation
Synthesis of gem-difluoromethylenated analogues of anamarine
Recent advances in the synthesis of fluorinated nucleosides
Coupling of sterically hindered aldehyde with fluorinated synthons: Stereoselective synthesis of flu
Palladium catalyzed direct alpha-arylation of alpha,alpha-difluoroketones with aryl bromides
Difluoromethylation of O-, S-, N-, C-Nucleophiles Using Difluorotri(n-butyl)ammonium Chloride as a N
From Difluoromethyl 2-Pyridyl Sulfone to Difluorinated Sulfonates: A Unique Protocol for Nucleophili
Highly Enantioselective Zinc(BINOL)-Catalyzed Alkynylation of ?-Ketoimine Esters
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Synthesis of ?-monofluorinated goniothalamin analogous via regio- and stereoselective ring-opening h
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Concise syntheses of trifluoromethylated cyclic and acyclic analogues of cADPR
Trifluoromethylated cyclic-ADP-ribose mimic: synthesis of 8-trifluoromethyl-N1-[(5’’-O-p
Direct Pd-Catalyzed Benzylation of Highly Electron-Deficient Perfluoroarenes
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Copper-mediated aerobic oxidative trifluoromethylation of terminal alkynes with Me3SiCF3
Copper-Mediated Oxidative Trifluoromethylation of Boronic Acids
Palladium-catalyzed cross-coupling of ethyl -fluoro- -bromoacetate with arylboronic acids: facile sy
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Diastereoselective Synthesis of Propargylic Fluorides and Its Application in Preparation of Monofluo
Highly Diastereoselective Synthesis of Quaternary ?-Trifluoromethyl ?-Amino Acids from Chiral Imines
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Polymer Electrolyte Membranes Based on Poly(norbornene)s with Pendant Difluoroalkyl Sulfonic Acids.
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Pd-Catalyzed Highly Regio- and Stereocontrolled Direct Alkenylation of Electron-deficient Polyfluoro
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Pd-Catalyzed Direct Cross-Coupling of Electron-Deficient Polyfluoroarenes with Heteroaromatic Tosyla
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Synthesis of Fluorinated β-Ketosulfones and gem-Disulfones by Nucleophilic Fluoroalkylations of
Difluoromethylenated polyhydroxylated pyrrolidines: facile synthesis, crystal structure and biologic
Copper-mediated oxidative cross-coupling reaction of terminal alkynes with ?-silyldifluoromethylphos
Synthesis of gem-difluoromethylenated analogues of boronolide
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C-F Bond Cleavage by Intramolecular SN2 Reaction of Alkyl Fluorides with O- and N-Nucleophiles
Copper and Phosphine Ligand-Free Palladium-Catalyzed Direct Allylation of Electron-Deficient Polyflu
Asymmetric synthesis of ?-aryl-?-trifluoromethyl-?-aminoarones via Mannich-type reactions of ketone
Copper-Mediated Fluoroalkylation Reactions with [(Phenylsulfonyl) difluoromethyl] trimethylsilane: S
Recent advances of trifluoromethylations
Copper Catalyzed Cross-Coupling of Iodobenzoates with Bromozincdifluorophosphonate
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Selective Fluoroalkylation of Organic Compounds by Tackling the ‘Negative Fluorine Effect
Palladium-Catalyzed Allylation of 2,2,2-Trifluoroethyl Phenyl Sulfone: A Potential 2,2,2-Trifluoroet
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Synthesis of fluoroalkylated allylic amine derivatives via palladium-catalyzed Overman rearrangement
Copper-Catalyzed Di- and Trifluoromethylation of α,β-Unsaturated Carboxylic Acids: A Prot
Regio- and Diastereoselective Nickel-Catalyzed Allylation of Aromatic Aldehydes with alpha-Halo-beta
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Nucleophilic Fluoroalkylation of a,β-Unsaturated Carbonyls with α-Fluorinated Sulfones: I
Nucleophilic Difluoromethylation of C=N Bonds in Heterocycles with Difluoromethyl Silane Reagents
Palladium-catalyzed direct ?-arylation of ?-fluoroketones: A straightforward route to ?-fluoro--aryl
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Pd-Catalyzed Dehydrogenative Cross-Coupling of Polyfluoroarenes with Heteroatom-Substituted Enones
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