中文摘要：

目的观察息肉样脉络膜血管病变（PCV）的临床特征。方法回顾性分析254例临床确诊的PCV患者306只眼的临床资料。所有患者均行矫正视力、裂隙灯显微镜、间接检眼镜、眼底彩色照相、荧光素眼底血管造影、吲哚青绿血管造影以及光相干断层扫描检查（OCT）。结果254例患者中，男性152例，占59．8％；女性102例，占40．2％。年龄38～91岁，平均年龄（65．4±8．9）岁。双眼52例，占20．5％；单眼202例，占79．5％。患眼矫正视力无光感～1．2。其中，矫正视力〈0．1者167只眼，占54．6％；≥0．1且〈O．3者92只眼，占30．10．4；≥0．3者47只眼，占15．4％。有玻璃体积血61只眼，占19．9％。202例单眼PCV患者中，另眼可见玻璃膜疣68例，占33．7％；渗出型老年性黄斑变性24例，占11．9％；对侧眼有中心性浆液性脉络膜视网膜病变病史9例，占4．5％。306只眼中，可见脉络膜高通透性表现43只眼，占14．1％。PCV病变位于黄斑区下199只眼，占65．0％；颞侧视网膜血管弓下49只眼，占16．0％；视盘旁15只眼，占4．9％。形态表现为孤立样110只眼，占35．9％；簇样176只眼，占57．5％；串样3只眼，占1．0％；分支样4只眼，占1．3％；既有孤立样同时也有簇样13只眼，占4．2％。存在神经视网膜下液性暗区125只眼，占40．8oA；出血性视网膜色素上皮脱离121只眼，占39．5％；浆液性视网膜色素上皮脱离73只眼，占22．9％。结论PCV双眼发病率、女性患病比例较高；病灶位于视盘旁比例较低。

英文摘要：

Objective To observe the clinical characteristics of polypoidal choroidal vasculopathy （PCV）. Methods Two hundreds fifty-four PCV patients （306 eyes） were enrolled in this study. All the patients were examined for corrected visual acuity （BCVA） testing, slit-lamp microscope, indirect ophthalmoscopy, fundus photography, fluorescein angiography, indocyanine green angiography and optic coherence tomography. Results The patients included 152 males （59.8%） and 102 females （40.2%）, the age was from 38 to 91 years, with a mean age of （65.4!8.9） years. Bilateral lesions were observed in 52 patients （20.5%） and unilateral lesions were observed in 202 patients （79.5%）. BCVA varied from non- light perception to 1.2. BCVA was lower than d0.1 in 167 eyes （54.6%）, 0.1 but d0.3 in 92 eyes （30.1%） and ~0.3 in 47 eyes （15.4%）. Vitreous hemorrhage was observed in 61 eyes （19.9%）. In 202 patients with unilateral PCV lesions, drusen can be observed in the contralateral eyes of 68 patients （33.7%）, exudative age-related macular degeneration changes in the contralateral eyes of 24 patients （11.9 %）, and central serous chorioretinopathy history was positive in the contralateral eyes in nine patients （4.5%）. In 306 eyes, there were 43 eyes （14.1%） with high permeable choroid. PCV lesions located at macula area in 199 eyes （65.0%）, under the temporal retinal vascular arcade in 49 eyes （16.0%）, and peripapillary in 15 eyes （4.9%）. PCV lesion formation was single in 110 eyes （35.9%）, cluster in 176 eyes （57.5%）, string in three eyes （1.0%）, branch in four eyes （1.3%）, and both single and cluster polyps in 13 eyes （4.2%）. There were 125 eyes （40.8%） with sub-neuroretinal fluid, 121 eyes （39.5%） with hemorrhagic pigment epithelium detachment, and 73 eyes （22.9%） with serous pigment epithelium detachment. Conclusion PCV patients have higher bilateral incidence and female prevalence, and lower rate of peripapillary lesions.