中文摘要：

肺癌是当今最常见的恶性肿瘤之一,各国的肺癌发病率和病死率近年都有明显增高趋势。肺癌高发与吸烟、空气污染、职业暴露、精神、遗传、饮食以及既往慢性肺部疾病等风险因素有关。本文介绍了几种常见的慢性肺部疾病,包括慢性阻塞性肺疾病、肺结核、特发性肺纤维化、硅沉着病等,总结了其与肺癌的关系,并试图阐明引起肺癌的可能的分子生物学机制,为探讨肺癌的病因提供依据。

英文摘要：

Lung cancer is one of the most common malignant tumors.In the recent decades,the incidence and mortality of lung cancer have significantly increased in all countries.The high incidence of lung cancer is associated with smoking,air pollution,occupational exposure,mental stress,heredity,diet and chronic lung diseases.This review introduces several common chronic lung diseases,including chronic obstructive pulmonary diseases,tuberculosis,idiopathic pulmonary fibrosis,silicosis,etc.In addition,this paper summarizes the relationship of chronic lung diseases to lung cancer and attempts to clarify the molecular biological mechanisms,which can provide a basis for investigating the etiology of lung cancer.