中文摘要：

目的比较单纯变应性鼻炎与合并下气道炎症的变应性鼻炎的抗炎治疗方案,探讨上、下气道联合治疗在短期内取得的疗效分析。方法选取2016年5-8月在新疆医科大学第一附属医院耳鼻喉科门诊确诊的变应性鼻炎103例,按照是否合并下气道炎症分为单纯变应性鼻炎（AR组）、变应性鼻炎合并气道高反应（ARAH组）、变应性鼻炎合并哮喘（AR＋ATHMA组）;AR组给予丙酸氟替卡松喷鼻＋鼻腔冲洗,ARAH组给予丙酸氟替卡松喷鼻＋鼻腔冲洗＋沙美特罗氟替卡松吸入剂（100μg/50μg）,AR＋ATHMA组给予丙酸氟替卡松喷鼻＋鼻腔冲洗＋沙美特罗氟替卡松吸入剂（250μg/50μg）,治疗1个月、3个月后随访对比,根据鼻内镜检查＋症状体征评分、鼻阻力＋肺功能测定结果评估疗效。结果治疗1个月、3个月后随访对比后发现,3组患者鼻部症状、体征都有不同程度的缓解,其中AR组较ARAH组和AR＋ATHMA组药物疗效明显;丙酸氟替卡松与沙美特罗氟替卡松吸入剂联合应用治疗AR＋ATHMA组患者症状控制短期疗效明显。结论变应性鼻炎应及早诊断或排除是否合并下气道炎症,确诊后根据不同类型实施治疗方案,必要时积极联合治疗,短期疗效显著;正确规范的诊疗流程可以减少临床误诊以及误治率,避免延误或过度治疗,能有效控制局部激素用量。

英文摘要：

Objective To compare the anti-inflammatory treatment regimens for the simple allergic rhinitis and airway inflammation merger of allergic rhinitis,exploring the therapeutic effect achieved within the short time of combined treatment of upper and lower airway.Methods A total of 103 patients with allergic rhinitis diagnosed in the Department of Otorhinolaryngology from the First Affiliated Hospital of Xinjiang Medical University from May 20 to August 2016 were divided into three groups according to whether the combined airway inflammation including simple allergic rhinitis（AR group）,allergic rhinitis airway hyperresponsiveness（ARAH group）and allergic rhinitis with asthma（AR＋ATHMA group）;treatment regimen for AR group was fluticasone propionate nasal spray nasal irrigation,ARAH group was given with fluticasone propionate nasal spray＋nasal wash＋salmeterol fluticasone inhalation（100μg/50μg）,AR＋ ATHMA group was given with fluticasone propionate nasal wash＋ nasal wash＋salmeterol fluticasone inhalation（250μg/50μg）for 1 month and 3 Months,between which follow-up was compared according to nasal endoscopy,and symptoms and signs score,nasal resistance and lung function test results.Result After the comparison of follow-up between 1 month and 3 months,the three groups of patients were observed to have different degrees of relief and amelioration in terms of nasal symptoms and signs.To be exact,the therapeutic effect was significantly improved in AR group compared with ARAH and AR＋ ATHMA groups;fluticasone propionate comobined with salmeterol fluticasone inhaler was shown to be best of all in terms of the therapeutic effect for AR＋ATHMA group,with the symptom being significantly relieved.Conclusion Patients with allergic rhinitis should go to hospital for diagnosis as earlier as possible.Treatment regimen should be carried out based on the different types of allergic rhinitis.Combined therapy could be used if necessary in light of its significant therapeutic effect within the short time.