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变应性鼻炎与血清25-羟维生素D水平的相关性
  • ISSN号:1009-5551
  • 期刊名称:《新疆医科大学学报》
  • 时间:0
  • 分类:R765.21[医药卫生—耳鼻咽喉科;医药卫生—临床医学]
  • 作者机构:新疆医科大学第一附属医院耳鼻咽喉科,乌鲁木齐830054
  • 相关基金:国家自然科学基金(81570896)
中文摘要:

目的检测变应性鼻炎(AR)患者血清25-羟维生素D的含量,明确AR与血清25-羟维生素D的相关性。方法收集2015年5月-11月新疆医科大学第一附属医院就诊的60例AR患者(AR组)的临床资料,同时选取60例健康体检者(对照组),采用化学发光法检测其血清25-羟维生素D值的浓度。结果 AR组的25-羟维生素D浓度值[(55.7±8.94)nmol/L]明显低于对照组[(80.65±12.06)nmol/L],差异有统计学意义(P〈0.05),AR组25-羟维生素D缺乏与不足所占的比例[8.3%(5/60)、91.7%(55/60)]明显高于对照组[71.7%(43/60)、28.3%(17/60)],差异有统计学意义(P〈0.05),AR患者中-重度组25-羟维生素D的浓度值[(49.81±4.48)nmol/L]明显低于轻度组[(60.86±8.71)nmol/L],差异有统计学意义(P〈0.05)。结论 AR与25-羟维生素D有关,AR患者25-羟维生素D的含量较正常人有所降低,且AR病情越重,25-羟维生素D的含量越低。

英文摘要:

Objective To study the content of 25-hydroxyvitamin D in patients with allergic rhinitis(AR),and to analyze the correlation between AR and 25-hydroxyvitamin D.Methods 60 cases of AR patients hospitalized from May 2015 to November 2015 in the First Affiliated Hospital of Xinjiang Medical University were selected as the AR group,and 60 healthy subjects were selected as control group,and the chemiluminescence method was used to test the content of the 25-hydroxyvitamin D.Results The concentration of 25-hydroxyvitamin D in AR group[(55.7±8.94)nmol/L]was shown to be significantly lower than that in the control group[(80.65±12.06)nmol/L](P〈0.05).The 25-hydroxyvitamin D level of AR group,the lack and deficiency of the number[8.3%(5/60),91.7%(55/60)]was found to be significantly higher than the control group[71.7%(43/60),28.3%(17/60)](P〈0.05).Concentration of 25-hydroxyvitamin D in moderate to severe group [(49.81±4.48)nmol/L]was significantly lower than that of mild group[(60.86±8.71)nmol/L](P〈0.05).Conclusion There was correlation existed between AR and 25-hydroxyvitamin D.Content of 25-hydroxyvitamin D in AR was found to be markedly lower than that in the normal control,indicating that the more serious the AR condition,the lower the content of 25-hydroxyvitamin D will be.

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期刊信息
  • 《新疆医科大学学报》
  • 中国科技核心期刊
  • 主管单位:新疆医科大学
  • 主办单位:新疆医科大学
  • 主编:哈木拉提.吾甫尔
  • 地址:乌鲁木齐市新医路393号
  • 邮编:830011
  • 邮箱:xjykdxxb@163.com
  • 电话:0991-4365141
  • 国际标准刊号:ISSN:1009-5551
  • 国内统一刊号:ISSN:65-1204/R
  • 邮发代号:58-100
  • 获奖情况:
  • 国家教育部优秀科技期刊三等奖,新疆优秀期刊奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),英国农业与生物科学研究中心文摘,中国中国科技核心期刊
  • 被引量:16959