1983年,让-皮埃尔·索瓦日将2个环形分子连接在一起形成链·并将其命名为索烃。2个互锁的环可以彼此相对移动,这是第一个分子机器的雏形。1991年,詹姆斯。弗雷泽’斯托达特制备了一种轮炕,并展示了分子轴上的分子环能够沿着轴移动。基于轮炕,他设计研发了分子电梯和分子肌肉等分子机器。1999年,伯纳德·费林加成为第一个开发分子马达的人,并且根据它设计制造出分子汽车。基于上述3位科学家在分子机器研究领域的杰出贡献,他们分享了2016年诺贝尔化学奖。
In 1983, Jean-Pierre Sauvage linked two ring-shaped molecules together to form a chain, called a catenane in which the two interlocked rings can move relative to each other. In 1991, Fraser Stoddart developed a rotaxane and displayed that the interlocked ring was able to move along the axle. Based on rotaxanes, he developed a few complex molecular machines, for instance, a molecular lift and a molecular muscle. In 1999, Bernard Feringa first developed a uni- directional, light-driven molecular motor which was further applied to design a nanocar. Sauvage, Stoddar and Feringa shared the Nobel Prize in chemisty in 2016 for the design and synthesis of molecular machines.