目的 探讨妊娠期生殖道感染对妊娠结局影响,以期提高临床对妊娠期生殖道感染患者的诊治水平.方法 选取2010-2013年医院行产前检查的妊娠期妇女为研究对象,其中生殖道感染阳性患者431例为感染组,根据感染组患者中有无症状变现和是否采取治疗再分为A、B、C、D组,另选取431例同期的生殖道感染阴性妇女为对照组;比较感染组与对照组患者的妊娠结局,另外对感染组患者依据有无症状和是否采取治疗同样进行分组比较,以此评价妊娠期生殖道感染对妊娠结局的影响.结果 不良妊娠发生率A、B、C及D组分别为26.62%、15.58%、39.82%及16.67%,B、D组的患者不良妊娠发生率略高于对照组的13.69%,差异无统计学意义;A、C组的不良妊娠发生率明显高于对照组,且C组的发生率还要高于A组,差异有统计学意义(P<0.05);新生儿并发症发生率感染组为62.88%,对照组为19.49%,组间比较差异有统计学意义(P<0.05).结论 生殖道感染患者的不良妊娠发生率和新生儿并发症发生率远高于未发生感染患者;抗菌药物治疗是针对可能导致不良妊娠结局的生殖道感染的主要治疗手段,可以有效的降低不良妊娠发生率.
OBJECTIVE To investigate the effect of reproductive tract infections during pregnancy on pregnancy outcomes in order to improve the level of clinical diagnosis and treatment of the reproductive tract infections during pregnancy. METHODS The pregnant women who underwent the prenatal examination in the hospital from 2010 to 2013 were enrolled in the study, 431 patients with reproductive tract infections were assigned as the infection group and divided into the group A, B, C, and D according to the change of symptom and the treatment status, meanwhile, 431 women without reproductive tract infections were set as the control group, then the pregnancy outcomes were compared between the infection group and the control group, finally the impact of the gestational reproductive tract infections on the pregnancy outcomes was evaluated by referring to the change of symptoms and the treatmenl status of the infection group. RESULTS The incidence rate of the adverse pregnancy was 26.62% in the group A, 15.58% in the group B, 39.82% in the group C, and 16.67% in the group D; the incidence rate of the adverse pregnancy of the group B and D was slightly higher than that of the control group, the difference was not significant; the incidence rate of the adverse pregnancy of the group A and C was significantly higher than that of the control group, and the incidence rate of the group C was higher than that of the group A, the difference was significant (P 〈0. 05). The incidence rate of complication in neonates was 62. 88% in the infection group, 19.49% in the control group, the difference between the two groups was significant(P〈0. 05). CONCLUSION The incidence of adverse pregnancy and the incidence of complication of neonate of the patients with reproductive tract infections are significantly higher than those of the patient without infections. The drug therapy is the predominant approach for the treatment of reproductive tract infections that may induce the adverse pregnancy and can effectively reduce the incidence of