中文摘要：

支架内血栓（ST）形成是经皮冠状动脉介入术治疗后少见的,但却是严重的甚至危及生命的并发症。与金属裸支架相比,药物洗脱支架已使再狭窄的发生率降低,但却使术后ST形成的发生率升高。支架内皮化不全或不内皮化是导致血栓形成的主要原因之一,如何提高支架的内皮化是临床研究的热点。研制新型抗血小板药物、提高支架置入水平,研发新型支架、基因治疗、重视冠心病的二级预防等是预防ST形成的有效措施。

英文摘要：

Stent thrombosis（ST） is a complication after percutaneous coronary intervention. It is rare, but is serious and even life-threatening. Compared with bare-metal stent, drug-eluting stent has reduced the incidence of restenosis,but has a higher incidence of stent thrombosis. One of the main reasons leading to thrombosis is incomplete endothelialization or unendothelialization, and how to improve stent endothelialization is a hotspot in clinical. The effective measures to prevent ST include ： developing new antiplatelet agents, improving the level of stent placement, researching new scaffolds, gene therapy, emphasis on the secondary prevention of coronary heart disease.