中文摘要：

目的：应用主成分Logistic回归分析法研究喀什市3~5岁维吾尔族儿童口腔龋病与白色念珠菌检出情况及危险因素的相关性。方法：采用分层整群抽样的方式随机抽取喀什市397名3~5岁维吾尔族健康儿童作为研究对象,对其进行口腔检查及采集牙菌斑,通过分离纯化培养及聚合酶链反应检测白色念珠菌检出情况。同时采用问卷调查家长对儿童的喂养方式、饮食习惯等。对白色念珠菌的检出情况,是否长期使用奶瓶、是否经常吃零食等20个婴幼儿龋病相关危险因素,采用方差极大正交旋转法进行主成分Logistic回归分析。结果：主成分分析结果显示特征值大于1的因子数目有7个,分别为：细菌因素、喂养/饮食习惯和家族史因子、宿主因素作用因子、口腔卫生习惯作用因子、社会经济背景作用因子、牙周状况作用因子、使用牙线、和性别因子,对总方差的累积贡献率为70.027%。经Logistic回归分析得出牙周状况和性别无统计学意义,其他因子均与婴幼儿龋病密切相关。结论：喀什市儿童龋病的发生是由多种因素共同作用的结果,除宿主自身因素、饮食习惯等因素外,白色念珠菌的检出也与龋病密切相关。运用主成分分析法构建的综合评价模型可以消除原始变量间的信息重叠,精简数据,客观、合理、综合地评价婴幼儿龋病危险因素的相关性,为当地儿童龋病的防治提供理论依据。

英文摘要：

Objective：To invesgate the correlation bewteen the detection of oral candida albicans and dental caries related factors among 3-5years of Uighur old children in Kashi City,and to provide scientific basis for children caries prevention.Methods：Using stratified cluster random method we collected dental plaque from caries tooth tissue and supragingival plaque samples from 397 healthy children aged 3-5years of Uighur in Kashi City.Data were collected by questionnaire from their parents and oral condition were clinically examined.The candida albicans were isolated,purified and identified by polymerase chain reaction.Principal component analysis logistic regression was used to analyze Candida albicans detection situation,whether long-term use of baby bottles,and the risk factors for early childhood caries.Results：Principal component analysis showed that there were seven risk factors,cumulative contribution rate of 70.027% of the total variance.Logistic regression analysis showed that,except the periodontal status and gender,other factors were closely related with early childhood caries.Conclusion：The incidence of early childhood caries is the result of many factors,especially,the detection of Candida albicans is closely associated with dental caries.Using principal component analysis to build a comprehensive evaluation model can eliminate overlapping information of the original variables,streamline data,objective,reasonable and comprehensive evaluate early childhood caries risk factors and provide a theoretical basis for caries prevention.