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生酮饮食治疗儿童难治性癫痫的前瞻性研究
  • ISSN号:2095-428X
  • 期刊名称:《中华实用儿科临床杂志》
  • 时间:0
  • 分类:R742.1[医药卫生—神经病学与精神病学;医药卫生—临床医学]
  • 作者机构:[1]Department of Paediatrics, Peking University First Hospital, Beijing 100034, China
  • 相关基金:This work was supported by the grants from the National Natural Science Foundation of China (No. 30571969) and the Natural Science Foundation of Beijing (No.7063096).
中文摘要:

在正常题目和癫痫的病人的背景脑电图( EEG )活动仔细经常与眼睛象眼睛那样的地位有关被打开( EO ),眼睛闭合( ECL )和眼睛关门了( EC ) .ECL 在如果只要眼睛是 ECL 导致的 EEG 上的 closed.Epileptiform 变化或 EC 被称为变化,眼睛遗体 closed.EC 是 pened ,比 3 秒为鹰的脚带眼睛和仅仅 Iasts 关门以后立即是时期 ECL 敏感( ECLS )或 EC 敏感( ECS ), .ECLS 主要发生然而并非 exclu

英文摘要:

Background Electroencephalogram (EEG) activity in normal subjects and epileptic patients is often closely related to the eye's status such as eye opened (EO), eye closure (ECL) and eyes closed (EC). ECL is the period immediately after closing of the eyes and only lasts for less than 3 seconds if the eyes remain closed. EC is the period as long as the eyes are closed. Epileptiform changes on EEG induced by ECL or EC are called the changes of ECL sensitivity (ECLS) or EC sensitivity (ECS). ECLS occurs mainly but not exclusively in photosensitive patients and ECS has been seen rarely in photosensitive patients. This study aimed to investigate the relationships among ECLS, ECS, photosensitivity and epilepsy syndromes in children. Methods EEG records from child patients in the EEG Department of Peking University First Hospital during the period of May 2005 to May 2007 were examined for the presence of ECLS or ECS. Open-close eye tests and intermittent photic stimulations were carried out during video-EEG monitoring for examining ECLS, ECS and photosensitivity. Results Based on ECLS and ECS on their EEGs, 30 patients were divided into ECLS group (16 cases) and ECS group (14 cases). There were more boys than girls in the two groups. The mean age of initial detection of ECLS and ECS was 10 years, and the average onset age of seizures was 9 years. The epilepsy syndromes in the ECLS group included idiopathic photosensitive occipital lobe epilepsy, Panayiotopoulos syndrome, symptomatic occipital lobe epilepsy, juvenile myoclonic epilepsy, juvenile absence epilepsy, eyelid myoclonia with absences, epilepsy with grand mal on awakening and pure photosensitive epilepsy with mainly generalized tonic clonic seizures. Those in the ECS group were juvenile myoclonic epilepsy, idiopathic photosensitive occipital lobe epilepsy, Panayiotopoulos syndrome and Gastaut type-idiopathic children occipital epilepsy. Photosensitivity was detected in 88% of patients with ECLS and 29% of patients with ECS. Concl

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期刊信息
  • 《中华实用儿科临床杂志》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中华医学会
  • 主编:郭学鹏
  • 地址:河南省新乡市金穗大道东段新乡医学院
  • 邮编:453003
  • 邮箱:syqk@xxmc.edu.cn
  • 电话:0373-3029144 3831456
  • 国际标准刊号:ISSN:2095-428X
  • 国内统一刊号:ISSN:10-1070/R
  • 邮发代号:36-102
  • 获奖情况:
  • 中国科技论文统计源期刊,临床医学类核心期刊,河南省优秀科技期刊二等奖
  • 国内外数据库收录:
  • 波兰哥白尼索引,中国中国科技核心期刊,中国北大核心期刊(2004版),中国北大核心期刊(2008版),中国北大核心期刊(2011版),中国北大核心期刊(2014版)
  • 被引量:5061