目的:探讨乳腺癌的中医证型分布及用药规律。方法:检索2000—2015年中国期刊全文数据库、维普数据库、万方数据库关于中医药治疗乳腺癌的相关文献,提取纳入文献的中医证候及用药信息,进行统一规范化处理后,建立乳腺癌中医治疗数据库,对其临床证候类型及用药情况进行相关频次分析。结果:纳入的45篇中医药治疗乳腺癌的文献中,中医证型主要为肝郁型、痰瘀毒热型、气血两虚型、冲任失调型、气阴两虚型,所占比例依次为48.4%、18.8%、15.6%、14.1%、3.1%;中药治疗乳腺癌的高频药物中归肝经的药物频率达33.3%。结论:在中医药辅助治疗乳腺癌的过程中从肝论治占主导地位。
Objective: To explore TCM syndrome and medication rule of breast cancer. Methods: Relevant documents of TCM in treating breast cancer in CNKI, CQVIP and WanFang Data were retrieved from the year of 2000 to 2015. TCM syndromes and medication information in documents were extracted. Database of TCM in treating breast cancer were built after united and standardized management. Relevant frequency of clinical TCM syndrome and medication condition was analyzed. Results: All 45 documents of TCM in treating breast cancer were in- corporated at last, TCM syndromes can be divided into liver-stagnation type, phlegm-stasis type, Qi and blood deficiency type, incoordination between the Chong and Ren meridians type, Qi and Yin deficiency type, the rates were 48.4%, 18.8%, 15.6%, 14.1% and 3.1% in turn. The frequent rate of high-frequency medicines belonged to liver meridian in Chinese herbs for breast cancer reached to 33.3%. Conclusion: Treatment starting from liver occupies dominant status in the process of TCM in treating breast cancer.