室内环境风险因素暴露对儿童哮喘发作和哮喘症状加重有不利影响.本文分析亚洲地区主要室内空气污染物暴露与儿童哮喘患病之间的关系,和该暴露对哮喘症状加重影响的最新进展.作者检索了PUBMED,Medline,Cochrane图书馆和会议论文集等数据库中与室内空气污染和亚洲儿童哮喘患病之间关系的相关文献做进一步流行病学研究.以往一致的证据显示室内空气污染增加了亚洲儿童哮喘、过敏和呼吸系统症状的患病率.但是,发表的文献指出由于各种物理、人为等因素对室内空气质量的影响,室内污染物暴露水平呈现不断变化.与儿童哮喘发病密切相关的主要室内空气污染风险因素包括:空气颗粒物,二氧化氮,被动吸烟和空气中的动物源性过敏原.针对这些风险因素造成的室内空气污染,已经制定了一些有效的预防措施.亚洲儿童室内环境暴露于空气污染有害因素比较普遍;如果给予适当的预防管理措施,环境暴露可以减少.然而,减少暴露是否会降低亚洲儿童哮喘患病及哮喘症状加重还未见文献报道.
Exposure to indoor environmental risk factors tion. This review analyzes the relationship between indoor may increase children asthma outbreak and exacerba- air pollutants and children asthma morbidity and the latest development in the impacts of indoor risk exposure on the exacerbations of asthma - related symptoms a- mong children in Asia. PUBMED, Medline databases, the Cochrane Library and conference proceedings were searched for epidemiologic studies pertaining to indoor air pollution and asthma morbidity among children in A- sia. There is consistent evidence that indoor air pollution increases the risk of asthma, allergy and respiratory symptoms in children. However, the published data show that levels of environmental exposures are highly varia- ble due to the effects of variety of physical, structural and behavioral factors on indoor exposures levels. Indoor air pollution risk factors mainly associated with children asthma morbidity include particulate matter, nitrogen diox- ide, tobacco smoke and airborne animal allergen exposure. Effective measures to prevent exposures to these pollu- tants are available. Children exposure to indoor risk factors in indoor environments is common in Asia. With prop- er management,the amount of environmental exposures could be decreased. Whether the decreased exposure re- suits in the reduced asthma prevalence and exacerbation is not yet documented.