中文摘要：

目的 了解鲍曼不动杆菌的临床分布特征及其对常用抗菌药物的耐药性,为临床合理用药提供参考.方法 回顾性分析我院2010-2012年临床分离的鲍曼不动杆菌的分布情况和耐药性变迁.结果 在检出的316株鲍曼不动杆菌中,临床标本来源以痰液为主,占74.1％;临床科室分布以重症监护病房（ICU）为主,占39.6％;在所测试的抗菌药物中,其耐药性总体呈上升趋势并显示了多重耐药,尤其是ICU.结论 近3年来,我院鲍曼不动杆菌感染及耐药性总体呈上升趋势,以亚胺培南的耐药性上升较为明显,在耐药性监测中显示了多重耐药性,特别是ICU,需引起临床关注.

英文摘要：

Objective To understand the distribution characteristics and drug-resistance to the common antibiotics of Acinetobacter baumannii isolated from clinical offices, so as to provide reference to clinicians about reasonable medication. Methods The study was a retrospective review, the results of clinical distribution and drug resistance of A. baumannii from Jan 2010 to Dec 2012 in our hospital were analyzed. Results Of the 316 A cinetobacter baumannii isolates, 261 strains（74.1%） were isolated from sputum, 125 strains（39.6%） of A. baumannii were from intensive care unit（ICU）, and the drug resistance rate of A. baumannii to 13 kinds of antibiotics appeared increasing, even multi-drug resistant or pan-drug resistant, especially in the ICU wards. Conclusion The isolation rate of A. baumannii is increasing in recent 3 years in our hospital, as well the resistance rate to the common antibiotics, particularly to imipenem in the ICU, appearing multi-drug resistance, which should be concerned.