中文摘要：

目的 分析2010—2014年临床分离的鲍曼不动杆菌的临床分布和耐药情况,为临床合理的选用抗菌药物提供依据。方法收集近5年在安徽医科大学第一附属医院住院患者临床分离的鲍曼不动杆菌的相关资料,用SPSS17.0软件分析其分布特征及对抗菌药物的耐药情况。结果 在检出的603株鲍曼不动杆菌中,以重症监护病房（ICU）最多（288株,47.8%）,其次是呼吸内科（12.9%）;标本以痰液最多（519株,81.1%）;在临床经常使用的抗菌药物中对头孢哌酮/舒巴坦较好的敏感性,耐药率为31.5%;对美罗培南、亚胺培南的耐药率较高（〉70%）。结论 鲍曼不动杆菌临床分布广泛、耐药情况严重,应加强对鲍曼不动杆菌的监测,为治疗和预防提供相关策略。

英文摘要：

Objective To analyze the clinical distribution and drug resistance of acinetobacter baumannii infection from 2010 to 2014, and to provide evidence for rational use of antibiotics in clinical practice. Methods A retrospective analysis was conducted. From 2010 to 2014,the clinical data of patients and the sensitivities of acinetobacter baumannii were collected in the first affiliated hospital of anhui medical university. The clinical distribution of acinetobacter baumannii and the drug resistance to the commonly used antibiotics were analyzed by SPSS 17. 0 software. Results Of the 603 strains of acinetobacter baumannii,288 strains （47. 8% ） were from intensive care unit （ ICU） followed by those from department of respiratory medicine （ 12. 9% ） . Most of the strains （519 strains,81. 1% ） were isolated from sputum specimens. Among the antibiotics often used in clinics,the drug resistance rate of acinetobacter baumannii to cef- operazone/sulbactam （31.5% ） was lower, while the drug resistance rates to imipenem, meropenem were higher than 70%. Conclu-sions acinetobacter baumannii is widely distributed in clinics, and the drug resistance is serious ; so w e should strengthen the monito-ring of acinetobacter baumannii, and provide relevant strategies for the treatment.