中文摘要：

探讨了在60 Co γ-射线辐照下水中阿莫西林的降解过程,考察了阿莫西林初始浓度、吸收剂量对其辐照降解的影响,利用LC-MS分析了阿莫西林的辐解产物,初步揭示了阿莫西林的降解途径.试验结果表明,γ辐照可有效降解水中的阿莫西林,初始浓度较低有利于阿莫西林的降解.阿莫西林的降解率随吸收剂量增大而增大,G值则随吸收剂量增加而降低,阿莫西林去除率随吸收剂量的变化呈指数关系.当阿莫西林的初始浓度为10 mg/L和100 mg/L,辐照剂量为15 kGy时,其降解率分别为100%和95.14%.阿莫西林经过辐照后主要存在6种辐解产物,其准分子离子质量分别为M＋H＋：278、384、382、336、340、294,初步推断其降解过程主要涉及羟基自由基的氧化.

英文摘要：

Amoxicillin was degraded by 60 Co gamma-ray irradiation in aqueous solution. The effects of initial concentration of amoxicillin and absorbed dose on degration of amoxi-cillin were investigated. The identification of radiolytical products has been conducted using high chromatography tandem mass spectrometry and possible pathways for further degration of amoxicillin were studied. Experimental results show that amoxicillin in aqueous solution can be effectively degraded by gammaray irradiation,especially in low-concentration. The amoxicillin degradation rate increased with increasing irradiation dose,whereas the Gvalue decreased,the relationship among amoxicillin removal and absorbed dose can be fit with index curve. Under irradiation dose of 15 kGy, the degration rate reached 100% and 95.14% at amoxicillin of 10 mg/ L,100mg/ L respectively. After irradiation,six major radiolytical products with [M ＋ H] ＋ 278,384,382,336,340,294 were produced,which were detected in several different conditions. Possible pathways for further degration of amoxicillin were studied. Degradation of amoxicillin induced by γ-radiation was mainly ascribed to ＆#183;OH oxidation.