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中文摘要：
合成并表征了一个新的Ru（Ⅱ）配合物[Ru（bpy）2（hedppc）]（ClO4）2{bpy=2，2′-联吡啶，hedppc=二联吡啶[3，2-a=2′，3′-c]吩嗪-11-羧酸（2-羟乙基）酯}．通过紫外-可见吸收光谱、与溴化乙锭竞争实验、粘度测量和DNA裂解实验研究了配合物与小牛胸腺DNA的相互作用性质．结果表明配合物以插入模式与DNA键合，键合常数Kb=（6．99±1．34）×10^6mol^-1·L（s=2．03±0．04）与母体配合物[Ru（bpy）2（dppz）]^2＋相近，但光致发光和溶剂变色等光学性质与[Ru（bpy）2（dppz）]^2＋有明显的差别．
英文摘要：
A new ruthenium（II） polypyridyl complex of [Ru（bpy）2（hedppc）]（ClO4）2 {in which bpy= 2,2′-biyridine, hedppc=2-hydroxyethyl dipyrido[3,2-a：2′,3′-c]phenazine-ll-carboxylate} was synthesized and characterize.d by elemental analysis, ^1H NMR and MALDI-TOF MS. The binding of the complex to calf thymus （ct） DNA was studied with UV-visible absorption and luminescence spectrophotometric titrations, DNA competitive binding with ethidium bromide, viscosity measurements and thermal denaturation experiments. The results indicated that the complex was bound to ct-DNA through an intercalative mode with an intrinsic binding constant of （6.99± 1.34）× 10^6 L/mol in buffered 50 mmol/L NaCl comparable to parent [Ru（bpy）2（dppz）]^2＋. The complex is permanently non-emissive in the absence and presence of the DNA, and exhibits intriguing solvatochromic properties different from parent [Ru（bpy）2（dppz）]^2＋.
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