中文摘要：

毛细管电泳（CE）技术是研究生物分子之间或生物分子与其他小分子之间相互作用的主要方法之一,而基于生物大分子（多糖、核酸、蛋白质、酶）或生物大分子组装体（细胞膜、细菌、活细胞）与目标分子间的相互作用研究,已发展出潜在活性药物筛选、手性药物对映体拆分及物质检测（分子识别）等方面应用的CE方法。本文对不同种类生物材料包括多糖、核酸、蛋白质、酶、细胞膜、细菌和活细胞在CE中的应用进行综述,以期为生物材料在CE中进一步应用研究提供参考。

英文摘要：

Capillary electrophoresis （CE）is one of the primary methods for investigation of the interactions between bio-macromolecules or bio-macromolecules with other small molecules. Based on the interactions of bio-macromolecules （ such as polysaecharides, nucleic acids, proteins and enzymes ） and bio-macromolecule assemblies （ such as cell membrane, bacteria and living cells ） with the target molecules, several CE methods have been developed for bioactive compounds screening, chiral drugs enantiomer separation as well as molecular recognition detection. In this paper, the applications of diverse bio-materials in CE were reviewed, including polysaccharides, nucleic acids, proteins, enzymes, cell membrane, bacteria as well as living cells, to provide scientific basis for their further study.