目的:了解上海市民政系统精神病医院住院慢性精神疾病患者共病躯体疾病状况。方法:采用自制《病例收集表》调查上海市民政系统精神病医院住院的所有精神疾病患者合并躯体疾病情况及影响因素。结果:1 707例患者中900例(52.7%)共病躯体疾病;前6位依次为高血压病(349例,20.5%)、糖尿病(204例,12.0%)、贫血(145例,8.5%)、心律失常(141例,8.3%)、白细胞减少症(131例,7.7%)及冠心病(120例,7.0%);共病躯体疾病1种600例(35.2%),2种228例(17.0%),≥3种72例(4.2%);共病率随患者年龄及住院时间增加显著增高(P〈0.01或P〈0.05)。服用抗精神病药患者糖尿病和心律失常的共病率明显高于未服药患者(P〈0.05或P〈0.01);服用第二代抗精神病药患者心律失常和冠心病共病率明显高于服用第一代药患者,白细胞减少发生率明显低于服用一代药患者(P均〈0.05);联合用药患者心律失常及冠心病发生率明显高于单一用药者(P〈0.01或P〈0.05);躯体疾病共病为因变量的回归分析显示患者年龄及服用抗精神病药数量进入模型(P均〈0.01)。结论:民政系统长期住院的慢性精神疾病患者躯体疾病共病率高,以高血压病、糖尿病、贫血、心律失常和白细胞减少症常见;年龄及服用抗精神病药数量是其影响因素;对共病躯体疾病的患者更应单一用药。
Objective: To analyze the current situation of accompanying somatopathy in inpatients with mental disorders in Shanghai civil psychiatric hospitals(SCPHs). Method:Using self-made case report form, the current situation and influencing factors of accompanying somatopathy in all the inpatients with mental disor- ders in SCPHs were investigated and analyzed. Results:Among 1 707 cases,there were 900 cases (52.72%) accompanying somatopathy. Among the top six diseases were hypertension (349 cases,20.5% ) ,diabetes melli- his ( 204 cases, 12.0% ) ,anemia ( 145 cases,8.5% ) ,arrhythmia ( 141 cases,8.3% ) ,leukopenia ( 131 cases, 7.7% ) ,and coronary heart disease ( 120 cases,7.0% ). There were 600 cases (35.2%) accompanying one kind,228 cases ( 17.0% ) accompanying two kinds and 72 cases (4.2%) accompanying 〉/3 kinds somatopa- thy. Comorbidity rates were increased significantly with the patientg age and duration in hospital stay(P 〈 0.01 or P 〈 0.05 ), Comorbidity rates of diabetes and cardiac arrhythmias in patients treated with antipsychotics were significantly higher than the patients treated without antipsychotic ( P 〈 0.01 or P 〈 0.05). Comorbidity rates of a~Thythmia ant] coronary heart disease in the patients treated with the second generation antipsychotics were sig- nificantly higher,the incidence of ]eucopenia was significantly lower than the patients treating with the first gen- eration antipsychotics ( all P 〈 0.05 ). Comorbidity rates of arrhythmia and coronary heart disease in the patients treated with drug combination were significantly higher than the patients treated with single drug ( P 〈 0.01 or P 〈 0.05 ). The rate of accompanying somatopathy was positively correlated with patients age, and negatively c, orrelated with nmnber of antipsychotic drugs ( r = 0. 161, r = -0. 143, all P 〈 0.01 ). Conclusion:The rate of accnmpanying somatopathy in inpatients with chronic mental disorders in SCPHs is higher;hypertension,