中文摘要：

克罗恩病是一种病因尚不清楚的胃肠道疾病,近年来我国克罗恩病的发病率呈上升趋势。白介素-33（IL-33）是近期发现的白介素-1（IL-1）家族中的新成员,其受体是ST2,IL-33/ST2途径在机体多种疾病的发病过程中发挥重要作用,越来越多的研究发现其与克罗恩病的发生也有一定的关系。本文简述了IL-33在克罗恩病中的研究发现。

英文摘要：

Crohn’s disease（CD） is a gastrointestinal disease, and the precise etiology of CD is still unclear.In recent years the incidence rate of CD has been increasing in China. Interleukin-33（IL-33） as the new member of interleukin-1（IL-1） family was found recently, and its receptor is ST2. IL-33/ST2 passageway plays a role way in the pathogenesis of various diseases, more and more studies exhibits it is also involved in the pathogenic course of CD. This paper narrates the research progress about IL-33 participating in CD.