哺乳动物在冬眠过程中表现出自发性低代谢是一种独特的应对不良环境的适应机制,该机制能够保护有机体不受各种有害事件的侵害。非冬眠哺乳动物,包括人类通常都不表现自发性的低代谢,人们试图从冬眠哺乳动物的自发性低代谢中学习如何诱导人类的低代谢。尽管控制低代谢的确切因素仍然不十分清楚,但是所有哺乳动物的自发性低代谢都具有低体温和低代谢的特征。并且人们已经证实了动物自发性低代谢不是特殊基因而是与人类共有的基因控制的,这就为诱导人类及其他哺乳动物的低代谢提供了一定的理论基础。利用与这2个特征相关的一些原理和因素,人们已经掌握了一些人工诱导低代谢的技术与方法。随着这些技术和方法的日臻成熟与完善,低代谢的人工诱导将在太空探索和生物医学等方面起到极其重要的作用。
Spontaneous hypometabolism during hibernation of hibernant mammals is a unique adaptation mechanism that protects organisms from various harmful events.But non-hibernant mammals,include human beings,do not show hypometabolism spontaneously.Researchers try to know how to induce human and non-hibernant mammals enter into hypometabolism state.Although the precise factors controlling hibernation remain unknown,all the hibernant mammals show two common features of low body temperature and low metabolic rate.People have confirmed that the spontaneous hibernant animals and humans share common genes which control hypometabolism.That confirmation provided some theoretical basis for induced hypometabolism in humans and other mammals.According to these two common features,people have tried a number of techniques and methods to induce hypometabolism in animals.As these techniques and methods is becoming matured and perfected,induced hypometabolism will be practice in human beings and play a vital role in the space exploration and bio-medicine.