中文摘要：

转化生长因子β诱导基因22（transforming growth factor β-inducible gene 22,TSC-22）是一个候选的负性生长调控和肿瘤抑制基因。能与其他转录因子相结合,参与细胞生长、凋亡等重要生命活动调控,在多种肿瘤中低表达,可能与多种肿瘤的发生、发展有关。

英文摘要：

Transformation growth factor β-inducible gene 22（TSC-22） is a putative negative growth regulation and tumor suppressor gene.It has the ability to combine with other transcription factors to regulate the cell growth and apoptosis.TSC-22 is lowly expressed in many types of tumors,which may be related to the tumorgenesis and development.